Why does exercise reduce the risk of Alzheimer's disease?

Do you suffer from Alzheimer's disease? Regular exercise and staying Physical activity can help protect the structure and function of our brains as we age, meaning it can reduce the chances of developing certain neurodegenerative conditions, such as Alzheimer's disease.

Alzheimer's disease usually affects people aged 65 or older. However, it can occur in people as early as their thirties, forties, or fifties. This is called the early onset of Alzheimer's disease. This type of Alzheimer's disease affects less than 10% of all people with the condition, according to WebMD.

Researchers have known over the years the protective effect of exercise. However, the exact answer to why Alzheimer's affects the brain has remained a mystery. Mystery, but the recently published study has some answers.

Alzheimer's disease – Know All about It

Alzheimer's disease is a progressive neurological disorder that can lead to brain contraction also known as atrophy and can also gradually lead to the death of these brain cells.

Regular exercise can help fight this condition

The results of the study were published in the Journal of Neurology, where Nancy suggests that physical activity alters the activity of the brain's immune cells, reducing inflammation, as the brain is made up of a class of special immune cells known as microglia.

What are this Microglia?

According to experts, these cells continuously scan brain tissue for damage or infection and remove debris or dying cells, and they also help produce new neurons through a process known as neurogenesis, which is associated with learning and memory.

How do exercises help these cells?

In order to do their job, microglia need to shift from resting to active and here comes the role of exercise that activates the work of these cells?

Researchers have revealed for the first time a link between physical activity and glial cell activation in order to improve cognitive function in the human brain.

In a recent study published in the journal Neuron, researchers found that the hormone iricin, which circulates through the body during exercise, can help reduce deposits of a protein fragment termed amyloid beta in the brain cells of a patient.

According to Forbes, according to the study, these beta-amyloid deposits form a plaque inside the brain that scientists believe causes the characteristic symptoms of Alzheimer's disease, and to discover this link, the researchers applied iresin to a three-dimensional model of human cell culture for Alzheimer's disease.

Main background

Several studies that followed people for years and decades of their lives found that the most physically active participants were less likely to develop Alzheimer's disease later in life.

According to the Alzheimer's Association, which compiled 11 of these studies, regular exercise can reduce a person's risk of developing dementia by almost 30%, and for Alzheimer's disease specifically (Alzheimer's disease is a type of dementia), this risk can be reduced by 45%.

A study published by researchers from Australia, Illinois and Minnesota found completing puzzles, playing card games, playing chess, taking adult education classes and other challenging cognitive activities can reduce the risk of dementia over age 70 by up to 11%. In addition, in July, the first-of-its-kind drug was approved by the Food and Drug Administration, and Lecanemab, made by pharmaceutical companies Biogen and Eisai, aims to slow dementia by removing plaque in the brain, although some outside the FDA have expressed concerns about its safety.

Surprising fact

10 million new people are diagnosed with dementia worldwide each year, meaning a new case is detected every 3.2 seconds, according to Alzheimer's disease International, and that number is expected to nearly double every 20 years, with the highest increases recorded in developing countries.