Can antihypertensive drugs really cause cancer?

"Taking three kinds of antihypertensive drugs, how did I get cancer!"

Ms. Zhao is 38 years old, she often works overtime and her blood pressure is relatively high, so she has been taking three kinds of antihypertensive drugs. Three months ago, Ms. Zhao suddenly found that her blood pressure was "disobedient" and could not be lowered by the medication, but there was no problem in the community hospital.

Until recently, Ms. Zhao's legs were weak and dizzy at home, so she rushed to the hospital for a checkup.

Most adrenal tumors are benign tumors, but there is also the possibility of malignancy. After finding out about this tumor, Ms. Zhao's heart was cold, and she felt that it was caused by taking too many antihypertensive drugs, which not only failed to cure high blood pressure, but also led to cancer.

A. Antihypertensive drugs are a scam and cannot cure hypertension at all.

Hypertension medication originated in the 1940s when thiocyanates were mainly used to treat hypertension, but the antihypertensive effect was unstable and short-lived; ganglion-blocking drugs were used in the 1950s; anti-hypertensive drugs in the 1960s included central hypotensive drugs, beta-blockers, vasodilators and calcium channel blockers.

In the 1980s, angiotensin I-converting enzyme inhibitors and angiotensin II receptor-blocking drugs were introduced, which are more familiar as Prilosecs and tartans, which can effectively lower blood pressure and also reverse and prevent hypertension-induced cardiovascular conformation reconstruction.

In 1933, Mauricio Rocha Silva found that a patient bitten by a snake could not raise his blood pressure, and finally died of hypotensive shock. At that time, he thought that snake venom had a blood pressure-lowering substance in it.

After 45 years, several medical doctors took over the research in this direction, and Captopril was successfully developed, and today this drug, still occupies an important role in the clinic.

Why hypertension patients can only always take drugs to control, but also can not be cured?

Can cure hypertension needs to look at the specific circumstances, such as some secondary hypertension, as long as the cause is found and cured, it is possible to restore the normal blood pressure level; but some primary hypertension is mainly due to genetic, environmental, and other factors, usually irreversible, only through the use of antihypertensive drugs to lower blood pressure, so there is no way to cure.

Second, long-term consumption of antihypertensive drugs can cause cancer?

It is often believed by hypertensive patients that long-term consumption of high blood pressure is prone to cancer, is this true?

In a research paper published in the medical journal British Medical Journal in October 2018, it was concluded that the incidence of lung cancer was 14% higher after more than five years of use of the Pulley class of antihypertensive drugs compared to the Satan class of antihypertensive drugs.

Is it true that long-term use of antihypertensive drugs, especially those in the generic class, can cause cancer?

Professor Stephen Evans, a drug expert at the London School of Hygiene, explained that the observational study could not rule out other influences that were not measured, such as the possibility that patients taking Prilosec antihypertensive drugs might have alcohol-related diseases or be obese or overweight. So the medical credibility of this study is, in fact, not strong.

Third, why do some people take antihypertensive drugs but get cancer?

However, some patients were found to have cancer after taking antihypertensive drugs. This may be because some tumors themselves can cause elevated hypertension, such as kidney tumors, pheochromocytoma, adrenal cortisol adenoma, aldosterone-secreting adrenal adenoma and pituitary tumors that cause Cushing's syndrome, which may cause secondary hypertension.

In addition, poor blood pressure control can also increase the risk of cancer. There are more and more studies showing that there is a correlation between high blood pressure and cancer incidence and mortality, and one study found that the risk of cancer in hypertensive men is significantly higher by 10% to 20%. Therefore, if you find that your high blood pressure is suddenly not even controlled by medication, it is best to seek medical attention promptly.

Of course, this situation may also be a coincidence, after all, many risk factors that cause high blood pressure are also risk factors for cancer, such as smoking and drinking.

Don't do these things once you take antihypertensive drugs

Nowadays, there are more and more patients with hypertension, and many of them need to take antihypertensive drugs for a long time, but be careful not to do these things when taking antihypertensive drugs: 1.

1, take the medicine to eat and stop

Once diagnosed with hypertension, you need to receive treatment for life, once you stop treatment is likely to lead to blood pressure back to the level of hypertension, so hypertensive patients once they start taking antihypertensive drugs can not stop at will, not eat stop, to adhere to the medication on time, if the medication intermittently, resulting in frequent fluctuations in blood pressure, the harm is greater than the simple increase in blood pressure.

2、Only take the medicine, not do life management

Treatment of hypertension can not simply rely on medication, because the treatment of hypertension, including drug therapy and non-drug therapy, for low-risk hypertensive patients, can first take 1 to 3 months of non-drug therapy, while high-risk patients should not only adhere to drug therapy but also to do a good job of life management, change poor lifestyle.

3, medicine and grapefruit together

Grapefruit contains a substance called furanocoumarin, the substance can inhibit the body's cytochrome P450 enzyme, resulting in more drugs into the body, thereby increasing the concentration of antihypertensive drugs in the blood, which can easily lead to hypotension and headache, dizziness, loss of appetite and other symptoms. Therefore, do not eat grapefruit before and after taking antihypertensive drugs.

For patients diagnosed with hypertension, insisting on taking antihypertensive drugs is a safe and effective way to lower blood pressure and cannot be stopped at will.