What is Endogard Plus Used For?

Endogard Plus is a veterinary medicinal product designed to treat and control various parasitic infestations in dogs. Manufactured by Virbac, this broad-spectrum anthelmintic is effective against a range of internal parasites, including roundworms, hookworms, whipworms, and tapeworms. In this blog, we will delve into the specifics of Endogard Plus, its active ingredients, how it works, its benefits, and important considerations for its use.

Active Ingredients and Their Functions

Endogard Plus for dogs contains three active ingredients: febantel, pyrantel embonate, and praziquantel. Each of these components plays a crucial role in targeting different types of parasites.

1. Febantel: This is a pro-benzimidazole anthelmintic that is metabolized in the body to fenbendazole and oxfendazole. It disrupts the energy metabolism of parasites, leading to their death. Febantel is particularly effective against roundworms and whipworms.

2. Pyrantel Embonate: Pyrantel is a tetrahydropyrimidine derivative that acts as a neuromuscular blocking agent. It causes paralysis in parasites, which are then expelled from the host's body through natural processes. Pyrantel is effective against roundworms and hookworms.

3. Praziquantel: This is an isoquinoline-pyrazine derivative that works by causing severe spasms and paralysis of the parasites' muscles. It is highly effective against tapeworms, including species such as Dipylidium caninum and Taenia spp.

How Endogard Plus Works

Endogard Plus works by combining the actions of its three active ingredients to provide comprehensive protection against a wide range of parasitic infections. When administered, the tablet is absorbed into the dog's bloodstream, where it begins to target and eliminate parasites.

• Roundworms and Hookworms: Pyrantel embonate paralyzes these worms, making them unable to attach to the intestinal wall. They are then expelled from the body through feces.

• Whipworms: Febantel disrupts the energy metabolism of whipworms, leading to their death and subsequent expulsion.

• Tapeworms: Praziquantel causes severe spasms and paralysis in tapeworms, which are then digested and expelled.

Indications for Use

Endogard Plus is indicated for the treatment and control of mixed infestations with the following parasites in adult dogs and puppies:

• Roundworms: Toxocara canis, Toxascaris leonina

• Hookworms: Ancylostoma caninum, Uncinaria stenocephala

• Whipworms: Trichuris vulpis

• Tapeworms: Dipylidium caninum, Taenia spp

Dosage and Administration

The dosage of Endogard Plus is based on the weight of the dog. The recommended dosage is:

• Small and Medium Dogs: 1 tablet per 10 kg of body weight

• Large Dogs: 1 tablet per 35 kg of body weight

The tablets can be administered directly to the dog or mixed with food. It is important to follow the dosage instructions provided by the veterinarian to ensure effective treatment.

Benefits of Using Endogard Plus

1. Broad-Spectrum Efficacy: Endogard Plus is effective against a wide range of internal parasites, providing comprehensive protection for dogs.

2. Convenient Administration: The tablets can be easily administered, either directly or mixed with food, making it convenient for pet owners.

3. Safety: Endogard Plus is generally well-tolerated by dogs when used as directed. It can be used in puppies from 2 weeks of age and in pregnant and lactating bitches.

4. Prevention of Zoonotic Diseases: By controlling parasitic infestations in dogs, Endogard Plus helps reduce the risk of zoonotic diseases that can be transmitted to humans.

Important Considerations

While Endogard Plus is a highly effective and safe product, there are some important considerations to keep in mind:

1. Contraindications: Endogard Plus should not be used in dogs with known hypersensitivity to any of its active ingredients. It should also not be used simultaneously with piperazine compounds.

2. Adverse Reactions: Some dogs may experience transient loose stools, diarrhea, or vomiting after administration. These reactions are usually mild and self-limiting.

3. Special Precautions: It is important to follow good hygiene practices when administering the tablets. Wash hands thoroughly after handling the product. In case of accidental ingestion by humans, seek medical advice immediately.

4. Storage: Store Endogard Plus in a cool, dry place, away from direct sunlight and out of reach of children and pets.

Conclusion

Endogard Plus is a versatile and effective solution for the treatment and control of various parasitic infestations in dogs. Its combination of febantel, pyrantel embonate, and praziquantel ensures broad-spectrum efficacy against roundworms, hookworms, whipworms, and tapeworms. By following the recommended dosage and administration guidelines, pet owners can help ensure the health and well-being of their dogs.