Nexgard Chewables For Large Dogs – Complete Guide for Pet Parents

Fleas and ticks aren’t just a nuisance; they can spread harmful diseases that put your dog’s health at risk. If you’re a pet parent to a large breed, you know how important it is to find an effective, safe, and easy-to-give preventive. Nexgard Chewables for large dogs check all those boxes—making flea and tick protection simple and stress-free.

What is Nexgard?

Nexgard is a monthly chewable treatment designed to kill fleas and ticks. It’s made by Boehringer Ingelheim and contains Afoxolaner, a powerful ingredient that targets parasites’ nervous systems, killing them before they can reproduce or spread disease.

Why Large Dogs Need Special Protection

Large breeds like Labradors, German Shepherds, and Golden Retrievers spend a lot of time outdoors, increasing their risk of flea and tick infestations. Because of their size, they need the correct dosage—too little won’t work, and too much could cause harm. Nexgard offers specific chew sizes tailored for large dogs to ensure safe and effective protection.

Benefits of Nexgard Chewables for Large Dogs

Kills fleas fast before they can lay eggs

Eliminates ticks including black-legged ticks, Lone Star ticks, and American dog ticks

Tasty chewable that most dogs love (beef-flavored)

Convenient monthly dosing – no messy topical applications

How Nexgard Works

Nexgard’s active ingredient, Afoxolaner, attacks the parasite’s nervous system, causing hyperexcitation and death.

On fleas – starts killing within 4 hours, eliminating all within 24 hours

On ticks – effective within 48 hours of attachment

This quick action helps prevent diseases like Lyme disease and ehrlichiosis.

Dosage Guidelines for Large Dogs

Nexgard comes in different chew sizes based on weight. For large dogs weighing 25–50 kg (55–110 lbs), the right chewable strength is essential. Never split or combine doses without veterinary advice.

How to Administer Nexgard Chewables

Offer it like a treat—most dogs will chew it up happily.

If your dog refuses, hide it in food.

Make sure your dog swallows the entire chew.

Give the chew once every month on the same date for consistent protection.

Nexgard Safety for Large Dogs

Nexgard is FDA-approved and considered safe for dogs over 8 weeks old and weighing at least 4 lbs.

Possible side effects: vomiting, diarrhea, lethargy, or loss of appetite (usually mild and temporary).

Dogs with a history of seizures should be given Nexgard only under veterinary supervision.

Nexgard vs. Other Flea and Tick Treatments

Chewables vs. topicals: Nexgard avoids the mess of spot-on treatments.

Nexgard vs. Bravecto: Bravecto lasts 12 weeks, but Nexgard offers monthly flexibility.

Nexgard vs. Simparica: Both effective, but flavor and tolerance may differ by dog.

Can Nexgard Be Used with Other Medications?

Yes, Nexgard is often used alongside heartworm preventives like Heartgard or Sentinel. However, always check with your vet before combining medications.

How Long Does Nexgard Last?

One chew protects your dog for 30 days. If you miss a dose, give it as soon as possible and return to your regular schedule. Skipping doses can leave your dog vulnerable.

Common Myths About Nexgard

“Nexgard isn’t safe.” – False; it’s FDA-approved and widely used.

“Natural remedies work just as well.” – Most natural options can’t eliminate heavy infestations.

“Big dogs don’t need flea prevention.” – In reality, large breeds are just as prone to infestations.

Tips for Effective Flea and Tick Control Beyond Nexgard

Bathe and groom your dog regularly

Wash bedding and vacuum your home often

Keep your yard trimmed to reduce tick habitats

Use year-round preventives to avoid seasonal spikes

Conclusion

For pet parents of large dogs, Nexgard Chewables offer a reliable, easy-to-administer solution to protect against fleas and ticks. With fast action, proven safety, and monthly convenience, Nexgard ensures your furry giant stays happy, healthy, and pest-free. Always consult your veterinarian for the best preventive plan tailored to your dog’s needs.

FAQs

1. Can Nexgard be given to puppies?

Yes, but only if they’re over 8 weeks old and weigh at least 4 lbs.

2. How soon does Nexgard start working?

It starts killing fleas within 4 hours and ticks within 48 hours.

3. What if my dog vomits after taking Nexgard?

Contact your vet—sometimes a replacement dose may be needed.

4. Can Nexgard be used all year round?

Yes, consistent monthly dosing provides year-round protection.

5. Is Nexgard safe for pregnant or lactating dogs?

Safety hasn’t been established for breeding, pregnant, or lactating dogs—consult your vet.