Credelio Plus for Dogs: The Complete Guide to All-in-One Protection

If you’re a dog parent, you know how important it is to protect your furry friend from fleas, ticks, and worms. These pests can cause serious discomfort—and even life-threatening illnesses. Luckily, there’s a single solution that takes care of it all: Credelio Plus for dogs.

In this guide, we’ll walk you through everything you need to know about Credelio Plus, how it works, its benefits, and why vets recommend it as one of the most reliable all-in-one parasite preventives for dogs.

What is Credelio Plus for Dogs?

Credelio Plus is a monthly chewable tablet designed to protect dogs from fleas, ticks, heartworms, and intestinal worms. Developed by Elanco Animal Health, it’s an upgraded version of the original Credelio, combining two powerful active ingredients for comprehensive protection.

Just one chew a month keeps your dog safe from some of the most common (and dangerous) parasites out there.

How Does Credelio Plus Work?

Credelio Plus combines the power of Lotilaner and Milbemycin Oxime. Lotilaner targets external parasites like fleas and ticks, killing them quickly and effectively. Meanwhile, Milbemycin Oxime works inside your dog’s body to eliminate internal parasites like roundworms, hookworms, and whipworms, while also preventing heartworm disease.

Together, they form a dual-action defense system that keeps your dog fully protected—inside and out.

Active Ingredients in Credelio Plus

4.1 Lotilaner

Lotilaner is an isoxazoline compound that targets the nervous system of external parasites. It starts killing fleas within 4 hours and ticks within 8 hours after administration.

4.2 Milbemycin Oxime

This ingredient is responsible for fighting internal parasites and preventing heartworm disease. It disrupts the nerve transmission in worms, effectively killing and controlling them before they can cause harm.

Key Benefits of Credelio Plus

5.1 Fast-Acting Flea and Tick Protection

Credelio Plus eliminates fleas before they can lay eggs, preventing infestations in your home. It’s also highly effective against major tick species like the Brown Dog Tick and Paralysis Tick.

5.2 Complete Worm Control

It kills and controls roundworms, hookworms, and whipworms, ensuring your dog’s gut stays healthy.

5.3 Heartworm Prevention

One of the standout features of Credelio Plus is its ability to prevent heartworm infection, a potentially fatal disease spread by mosquitoes.

5.4 Convenient Chewable Format

The tasty chew is easy to administer and loved by dogs. You can give it directly or mix it with food—no mess, no stress!

Why Choose Credelio Plus Over Other Treatments

Unlike some single-action treatments, Credelio Plus offers broad-spectrum protection against multiple parasites with just one chew.

It’s an all-in-one solution that replaces the need for separate flea, tick, and worming products, making it both cost-effective and time-saving.

How to Use Credelio Plus

7.1 Choosing the Right Dosage

Credelio Plus comes in multiple variants depending on your dog’s weight:

2.8–5.5 kg

5.6–11 kg

11.1–22 kg

22.1–45 kg

45.1–60 kg

Always weigh your dog before selecting the dosage to ensure optimal protection.

7.2 How to Administer

Give one chewable tablet once a month. It can be administered with or without food, though giving it with a meal may improve absorption.

When to Start Credelio Plus for Puppies

Credelio Plus can be given to puppies from 8 weeks of age, provided they weigh at least 2.8 kg. Early protection helps prevent early-stage infestations and reduces the risk of developing parasitic diseases later.

How Often Should You Give Credelio Plus?

Administer one chew every month, ideally on the same date. Staying consistent ensures your dog stays fully protected year-round.

Pro tip: Mark the date on your calendar or set a monthly reminder!

Possible Side Effects

Most dogs tolerate Credelio Plus very well, but in rare cases, mild side effects can occur. These may include:

Vomiting

Diarrhea

Loss of appetite

Lethargy

If any unusual symptoms persist, contact your veterinarian immediately.

Safety Precautions and Warnings

Use only on dogs 8 weeks or older and weighing 2.8 kg or more.

Not for use in cats.

Store in a cool, dry place away from direct sunlight.

Always consult your vet before using Credelio Plus with other medications.

Credelio vs Credelio Plus: What’s the Difference?

Feature Credelio Credelio Plus

Flea and Tick Protection ✅ ✅

Heartworm Prevention ❌ ✅

Intestinal Worm Control ❌ ✅

Active Ingredients Lotilaner Lotilaner + Milbemycin Oxime

Type External parasite control All-in-one protection

If you want complete, inside-out protection, Credelio Plus is the superior choice.

Veterinarian Recommendations

Veterinarians highly recommend Credelio Plus for its efficacy, safety profile, and convenience. It’s a trusted product that simplifies parasite prevention, especially for multi-pet households.

Tips for Effective Parasite Prevention

Keep your dog’s bedding and environment clean.

Check your pet regularly for ticks, especially after walks.

Maintain a consistent dosing schedule.

Pair Credelio Plus with regular vet check-ups for maximum safety.

Conclusion

Parasite prevention doesn’t have to be complicated. With Credelio Plus for dogs, you get complete protection in one convenient chew. From fleas and ticks to heartworms and intestinal worms, this all-in-one treatment ensures your pet stays happy, healthy, and pest-free all year long.

Protect your pup today—because prevention is always better than cure!

FAQs

1. What parasites does Credelio Plus protect against?

It protects against fleas, ticks, heartworms, roundworms, hookworms, and whipworms.

2. Can I give Credelio Plus to my puppy?

Yes, if your puppy is at least 8 weeks old and weighs 2.8 kg or more.

3. How quickly does Credelio Plus start working?

It starts killing fleas within 4 hours and ticks within 8 hours after administration.

4. Can I use Credelio Plus with other treatments?

Always consult your vet before combining Credelio Plus with other medications.

5. What happens if I miss a dose?

Give the missed dose as soon as you remember and continue with the regular monthly schedule.