Is Too Little Sleep Making You Fat
Many of us are living at low level of sleep deprivation.

If you find yourself dragging during the day, what do you do? If you're like me, you snack. A snack boosts your blood sugar, giving you a quick energy boost, and your off and running. So it wouldn't be too surprising to find yourself snacking throughout the day to maintain your energy level. The downside is the extra calories you take in from snacking.
Sleep-Deprived Have Enhanced Ability To Smell Food
Scientists have already determined that sleep-deprived individuals crave high-calorie food. However, they didn't know why. Although you may question if scientists already knew this, what's so important about the why?
The why may point toward a strategy to circumvent the behavior.
Thorsten Kahnt, a neurologist from Northwestern University's Feinberg School of Medicine, may have discovered a key. The sense of smell in sleep-deprived volunteers is enhanced. Smell initiates appetite, as anyone walking into a bakery smelling fresh baked goods can attest to. Kahnt determined that the enhanced smell of the sleep-deprived also prefers high caloric food.
https://clinicaltrials.gov/ct2/show/NCT050934J3
The researchers put the sleep-deprived volunteers into an MRI to see how this was happening. While being scanned in the MRI, the volunteers were given a variety of smells of both foods and non-foods. While the piriform showed increased activity, the information flow between the piriform cortex and the insula decreased.
https://www.science.org/content/article/h ere-s -how-skimping-sleep-can-change-your-appetite
Why That Matters
The piriform cortex is the part of the brain that processes smell. In sleep-deprived individuals, this brain region shows more significant activity and is enhanced. Enhanced as in more sensitive to food smells.
The insula cortex is a multimodal part of the brain that regulates food processing. For example, the insula cortex integrates taste, olfactory, and somatosensory inputs.
While it is too early to define this as a cause and effect based on one experiment, it does invite more experiments to be performed.
Nevertheless, the results suggest that the enhanced smell and decreased communication between the piriform cortex and insula will tend to cause an individual to choose higher caloric foods.
Is The Loss of Sleep Making You Fat, Or Is Fat Making You Lose Sleep?
New research has come to light that might flip this around. Research from the University of Pennsylvania and published in PLOS Biology suggests excessive weight can cause poor sleep.
https:/www.sciencedaily.com/releases/2020/04/200422091205.htm
The research conducted on worms may not apply to humans: it is suggestive of the biochemistry involved and needs further investigation.
The researchers were studying the relationship between metabolism and sleep. A series of studies using genetically engineered worms that could not sleep, found that ATP levels decreased, and the worms became obese. Researchers focused on the worm's KIN-29 gene, thinking that the release of fat is promoted during sleep. 1%en researchers expressed an enzyme that freed fat from the worms, they could sleep again.
The KIN-29 is homologous to our human Salt-Inducible Kinase (SIK-3) gene, which is associated to signal sleep.
In my previous article on fat, "Understanding Fat The Secret To Getting Your Body Fat Under Control," fat is not an accumulation of inert cells.
Strategy Action Steps
About the Creator
John Iovine
Science writer


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