Millions of men have recently started
taking testosterone as a pill nasal
spray or injection with a new industry
booming in 2021 a survey found
testosterone supplementation is most
common amongst younger men now more than
ever before so why are so many men
huffing testosterone what is it doing to
your brain and body and is it linked to
a decrease in testosterone infertility
seen in men around the world so to start
we must understand testosterone
testosterone is a hormone hormones are
chemical Messengers in your body that
flow through your bloodstream and bind
to receptors on or in cells to stimulate
action and maintain your life hormones
are produced in endocrine glands in your
body such as the pituitary gland pineal
gland thyroid gland but your gonads also
produce hormones such as oestrogen from
the ovaries or testosterone from the
testes although testes do produce
oestrogen more on that later testosterone
is a steroid hormone so unlike protein
hormones which are made of amino acids
and bind to the out side of cells
steroid hormones like testosterone can
pass through lipid bilayers and enter
cells to have their effect after
conception before six weeks in the womb
no one had visible testes in fact
whether you are a woman or a man or
anything in between before six weeks
when you are in the womb everyone was
starting to grow a vagina when conceived
you receive an X chromosome from your
mom but depending on which of your dad's
sperm fused with the egg you either get
another X chromosome or a y chromosome
before six weeks all development is
controlled by the X chromosome but at
six weeks if you got a y chromosome the
scry gene encodes an sry protein which
changes the gonads the sry protein
causes the pre-ovaries to drop into
testes the labia's to fuse into the
scrotum creating that line of tissue on
the ball sack and the clitoris grows
into a penis so yes at first we all kind
of had vaginas then if the sry gene
kicked in you started to grow testes and
started to produce testosterone but
there are are exclusions to this process
because human sex is complicated you can
have X Y chromosomes and can appear
female with a vagina but have testes
internally due to conditions along
chemical Pathways that happen after six
weeks in the fetus this is known as
being intersex it proves that the binary
of being XX of women and X Y A man is
not real for the most part if you are XY
the production of testosterone will
begin to change your life as your
pituitary gland will release a hormone
called GnRH which will stimulate the
production of testosterone in the testes
the GnRH hormone is decreased during
childhood but when a person with testes
starts to go through puberty around the
ages of 9 to 14 the GnRH hormones are
subpulsate again and things start to
change the first signs of puberty being
the testes increasing in size and
releasing more testosterone the increase
in testosterone is what causes the
masculinization of boys their voice
lowers they grow body hair start
producing sperm after puberty the testes
contain continued production of
testosterone is important to help
maintain bone density fat distribution
muscle strength facial hair growth sex
drive and of course continued sperm
production a feedback loop in the body
regulates the amount of testosterone
that flows through your blood if
testosterone gets too high a signal sent
to the pituitary gland to decrease
hormones which decrease testosterone in
your body for this reason testosterone
levels can vary quite a bit throughout
your life but also vary quite a bit
throughout the day this is one reason
why it can be so hard to Define normal
testosterone levels so why is it that so
many men are now playing with their
endocrine systems and adding
testosterone to their bodies first the
most common reason for testosterone
supplementation in older men is
hypogonadism known as a TDS testosterone
deficiency syndrome it's a common
condition in aging men but not many
people talk about it when a woman goes
through menopause there is a stark
decrease in the hormone estrogen from
their ovaries causing typical symptoms
such as hot flashes mood changes and
everyone loves to talk about that men
also go through a form of menopause as
they age there is a decrease in
testosterone from the testes and an
increase in the sex hormone globulin
which decreases bioavailable
testosterone but this decrease isn't
Stark this process is slow and gradual
and for this reason in many ways it goes
unnoticed it is completely normal and
most likely one will never lose enough
testosterone for it to affect them but
two to five percent of people with
testes over the age of 40 have
testosterone levels that are too low
leading to a TDS known as hypogonadism
symptoms include extreme fatigue
decreased sexual desire reduced body and
facial hair increased breast size poor
concentration brittle bones erectile
dysfunction and mood swings you can't
just say you have hypogonadism because
you feel those symptoms they could be
due to something else you have to have
your blood tested by a doctor for
testosterone levels to Define yourself
as having hypogonadism the concept of
testosterone replacement therapy was
developed over 75 years ago to treat
this condition and the Baltimore
longitudinal study of Aging reported the
incidence of hypogonadism as 20 in men
over 60 30 in men over 70 and 50 in men
over 80 years of age it's difficult to
diagnose again as we said testosterone
levels can vary so much throughout the
day so you could get a low testosterone
reading but not have the symptoms and
not have hypogonadism a doctor needs to
consistently look at your blood in order
to understand if you have this condition
but hypogonadism is not explaining why
so many young men are currently taking
testosterone one study of men entering a
health clinic found that 43 percent of
male respondents were interested in
testosterone replacement therapy but
only half of them were even aware of
what hypogonadism was they were not
there for this condition testosterone
supplements and therapy have increased
four-fold in the last 20 years for men
between the ages of 18 to 45. again
nothing to do with hypogonadism and it
is an increasingly popular and highly
marketable industry so why are so many
young men playing with their endocrine
system a good place to start is in 2000
and three when Harvard medical study
found that even among men who had normal
testosterone levels taking testosterone
supplements led to a loss of fat and
increase in muscle mass better overall
moods and less anxiety in magazines
health subreddits and YouTube videos it
is marketed as a remedy to aging and the
weakening male body there are studies
that show testosterone can increase bone
density and be a valid treatment for
age-related decrease in muscle mass by
increasing type 1 and type 2 muscle
fibers a study on Aging men with
hypogonadism found that testosterone
supplementation helped them bench press
more and leg press more Burrows
anecdotal evidence says that men who
take testosterone feel younger and more
sexual the most commonly reported
perceived benefits of testosterone
supplementations was improve sexual
function increased energy and quote
unquote feeling better in Rat models
castrated mice would have reduced
erectile function when testosterone
therapy was started in a castrated Mouse
erectile function improved studying men
with hypogonadism it was found that
testosterone therapy helped with sexual
ability morning erections and sexual
desire another survey found young men
used testosterone therapy for reasons
such as fatigue erectile dysfunction and
depression the issue is that now people
are seeking out testosterone replacement
therapy devoid of any connection to
their doctor there is a growing industry
now of people willing to sell you this
chemical without any testing therefore
many men are taking it without
understanding if they are actually
suffering from low levels of
testosterone it makes sense that you
might want to attribute your fatigue
depression lack of sexual desire to low
testosterone without actually really
knowing then reaching for a supplement
whose side effects might be you getting
jacked the thing is there are serious
risks that can come with taking
testosterone supplementation without
consulting your doctor especially if you
are young to start there is some very
confusing and conflicting research that
will change based on which studies you
are reading one study clearly stated
that testosterone therapy can increase
your risk of heart disease but this was
a very small study and a recent
meta-analysis which is a study of many
studies found that it had no effect on
cardiovascular disease if you had no
core morbidities going into the
supplementation testosterone companies
and people who are proponents of
testosterone supplementation will be
pointing at this meta-analysis a lot one
thing we know for sure is that
testosterone supplementation increases
hematocrit aka the amount of red blood
cells in your blood this is why it is
important to have blood tests and your
doctor monitoring your blood while
taking testosterone as your blood will
be getting thicker as well if blood cell
amounts get too high in your blood it
can lead to cardiovascular disease
stroke and Pulmonary embolisms
testosterone can stimulate the prostate
gland and prostate cancer to grow
leading many medical professionals to
worry about testosterone therapy leading
to prostate cancer but many other
longitudinal studies investigating the
relationship of testosterone levels and
subsequent risk of prostate cancer
failed to find any association although
one study found that it could make
already existing prostate cancer worse
but not technically create the prostate
cancer that's the conflicting research
now onto the risks that we do know are
real from taking testosterone
supplementation the biggest issue with
young people taking testosterone
supplements is decreased sperm count and
decreased fertility GnRH is the hormone
needed for spermatogenesis to occur when
you take increased testosterone it
blunts the release of GnRH decreasing
spermatogenesis and can even decrease
the size of the testes this is why
testosterone therapy can be okay for
older men with hypogonadism because
they've usually stopped trying to make a
family but if young men are taking this
supplement without talking to their
doctor to get bigger muscles to feel
better more sexual Etc they may not
realize that they're decreasing their
ability to start a family as well as
shrinking their balls in the last 40
years sperm counts have decreased by 50
percent leading to a huge fertility
issue with one-third of all infertility
issues being linked to sperm it's
important that young men understand take
taking testosterone could increase their
chance of being infertile as well we
have a video you can click above about
how the chemicals and Plastics and air
fresheners and fast food packaging are
actually decreasing sperm counts
decreasing taint size and in some ways
decreasing human penis size as well
shrinking balls and leading to decreased
fertility other issues with testosterone
supplementation could be increased risk
of breast cancer there are no direct
links right now as it is understudied
but the high levels of testosterone may
lead to a biochemical pathway that
stimulates increased breast tissue
receptors which could lead to increased
breast cancer one study of 45 men on
testosterone therapy found breast cancer
incidence of 11 but it's not significant
enough at this time to draw a
correlation this specific link is being
studied a lot right now as young men
taking testosterone is quite a new thing
so continue to look up on its effect on
breast cancer in the coming years an
increase in testosterone will also lead
to an increase in sebum causing acne
people on testosterone should monitor
how bad their acne can get testosterone
is supplementation also leads to
obstructive sleep apnea but the
biological pathway as to why is not
currently known if you already have
sleep apnea testosterone supplementation
can make it much worse and even create
it in people who start the
supplementation this can also lead to
sleep issues heart issues and insomnia
not to mention taking testosterone might
make you a nasty snorer testosterone
supplementation has also been linked to
kidney stones as well as more emotional
side effects such as mood swings
irritability and impaired judgment if
you have low testosterone or suffer from
hypogonadism testosterone replacement
therapy can be very beneficial to your
life the only way to know this is if you
go to a doctor and have your blood
tested consistently to understand if you
have low levels of testosterone there
are serious risks that come with taking
testosterone without any relation to
your doctor the popularity of
testosterone supplementation in young
men is continuing to grow It's All Over
YouTube it's all over like GQ Magazine
so we made a podcast with even more
detail about what is going on with this
really interesting way that men are
playing with their endocrine system so
we are going to continue to do our
research leave any questions below if
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