Md. Saiful Islam

Health

Immune T Cells and Exercise A recent study conducted by Harvard Medical School and published in Science Immunology has shed light on the connection between exercise and inflammation. This study, which was conducted on mice, suggests that the immune system plays a crucial role in the beneficial effects of exercise. The researchers found that exercise-induced muscle inflammation activates a specific type of T cells called Tregs. These Tregs are known for their ability to counter abnormal inflammation and have long been associated with autoimmune diseases. However, this study reveals that Tregs also play a significant role in the body's immune response to exercise. The presence of Tregs in the muscles is enhanced by regular exercise, leading to improved muscle metabolism and overall performance. These Tregs help the muscles utilize energy more efficiently, acting as a fuel source during exercise. Additionally, they contribute to increased exercise endurance. On the other hand, the absence of Tregs results in uncontrolled inflammation driven by interferon. This suggests that Tregs play a crucial role in mediating the body's response to exercise and preventing excessive inflammation. This study provides a molecular explanation for the century-old observation of increased white cell count in the blood of marathon runners after a race. It highlights the importance of Tregs in regulating inflammation and optimizing the benefits of exercise. Overall, this research deepens our understanding of the immune system's involvement in exercise and opens up new avenues for exploring the potential therapeutic applications of Tregs in improving exercise performance and managing inflammation-related conditions.