Humans logo
Content warning
This story may contain sensitive material or discuss topics that some readers may find distressing. Reader discretion is advised. The views and opinions expressed in this story are those of the author and do not necessarily reflect the official policy or position of Vocal.

Christina Applegate Shares How 'I Lay in Bed Screaming' from MS Pain

The actress revealed that her symptoms have “traveled into my hands” as she continues to struggle with multiple sclerosis

By Mian HamidPublished about a year ago 3 min read

Christina Applegate Shares How 'I Lay in Bed Screaming' from MS Pain

The actress revealed that her symptoms have “traveled into my hands” as she continues to struggle with multiple sclerosis

Christina Applegate Shares How 'I Lay in Bed Screaming' from MS Pain

Christina Applegate shared a raw look at the physical side of multiple sclerosis, talking about how the disease can often leave her “screaming” in pain.

“I lay in bed screaming — like, the sharp pains, the ache, that squeezing,” the Dead to Me actress said, revealing that her symptoms have progressed during the Nov. 5 episode of MeSsy, the podcast she cohosts with Jamie-Lynn Sigler, who also has MS.

Related :Hayley Erbert Reveals She Has 'a Medical Team Around' When She’s Dancing After Her Emergency Surgery

On the episode, the twosome spoke with Rory Kandel, the owner of Rory’s Bakehouse, who shared that her MS is also "manifesting as pain.”

“It feels like I have knives in my stomach,” Kandel said. “Like, I'll be laying in bed, and I wake up, and I physically can't turn from side to side.”

Christina Applegate Shares How 'I Lay in Bed Screaming' from MS Pain

“It's the worst,” said Applegate, who was diagnosed with multiple sclerosis in 2021. The Cleveland Clinic explains that the progressive disease “damages the protective cover around nerves called myelin in your central nervous system. It can cause muscle weakness, vision changes, numbness and memory issues."

“Do you feel like that?” Kandel asked, prompting Applegate to reply, “Every single day of my life.”

Related :Eva Mendes Gets Candid About Utilizing Beauty Treatments: 'There Have Been Times Where I’ve Regretted Something'

“I can't even pick up my phone sometimes because now it's traveled into my hands, so I'll, like, try to go get my phone or get my remote to turn on the TV or sometimes, I can't even hold them. I can't open bottles now.”

“But we look fine,” Kandel said.

“Because it's the beauty of the invisible disease,” Applegate said.

Related :Amber Tamblyn Recalls Getting Her Ears Pinned at 12, Despite Considering Herself a ‘Fiery Young Feminist’

Christina Applegate Shares How 'I Lay in Bed Screaming' from MS Pain

The Married...with Children alum shared that depending on her pain levels, “I just lay in bed all the time. I mean, I worked for almost 50 years, so I'm like, I'm kind of okay with it.”

Getting out of bed in the morning can be so painful that Applegate compared it to the “floor is lava. The floor is lava.”

“It looks like somebody put a hot fire poker up my a—hole,” Sigler said about those first steps of the day.

Related :Josh Brolin Praises Robert Downey Jr.’s Sobriety Journey After Reuniting at Broadway Show: ‘Love You, Pal’

“I put my feet on the ground and they're hurting, like, extraordinarily bad to the touch," said Applegate. "I was like, yep. Gonna get back in my bed and pee in my diaper because I don't feel like walking all the way to the damn bathroom,” she said, adding quickly, “I actually don't lay here and pee in my bed diaper. That's just a joke.”

“But it's like it's so freaking painful and so hard and so awkward.”

The Quran - Chapter An - Nazij'at : 42 - 44

They ask you ˹O Prophet˺ regarding the Hour, “When will it be?”

But it is not for you to tell its time.

That knowledge rests with your Lord ˹alone˺.

celebrities

About the Creator

Mian Hamid

Reader insights

Be the first to share your insights about this piece.

How does it work?

Add your insights

Comments

There are no comments for this story

Be the first to respond and start the conversation.

Sign in to comment

    Find us on social media

    Miscellaneous links

    • Explore
    • Contact
    • Privacy Policy
    • Terms of Use
    • Support

    © 2026 Creatd, Inc. All Rights Reserved.