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Will There Be Another Pandemic In Your Lifetime?

Will There?

By MarcosOPublished 3 years ago 3 min read

The occurrence of devastating pandemics like the Black Death, the 1918 Flu Pandemic, and COVID-19 may seem unlikely, but history tells us otherwise. Between 1980 and 2020, at least three diseases emerged that caused global pandemics: COVID-19, the 2009 swine flu, and HIV/AIDS. Disease outbreaks are surprisingly common, with the longest period without a documented outbreak resulting in at least 10,000 deaths lasting only four years over the past four centuries. While smaller outbreaks are distressing, they are considerably less deadly than a pandemic on the scale of COVID-19.

To determine the likelihood of experiencing a future pandemic, we can explore different approaches. One method involves analyzing historical data. A team of scientists and engineers studied documented epidemics and pandemics between 1600 and 1950, graphing the probability of an outbreak occurring somewhere in the world over a specific timeframe. They also estimated the likelihood of an outbreak becoming large enough to cause a certain percentage of the global population's death. This analysis revealed that while massive pandemics are improbable, they are not as unlikely as we may think. The team used these distributions to estimate that the risk of a pandemic similar to COVID-19 is approximately 0.5% per year and could increase to 1.4% if new diseases emerge more frequently in the future.

Another approach to estimating the likelihood of a future pandemic involves modeling it from the ground up. For a pandemic to occur, a pathogen needs to cross over from its animal host to humans and then spread widely across borders, infecting numerous individuals. Many factors influence whether a spillover event leads to a pandemic, such as the pathogen's type, frequency of human-animal contact, existing immunity, and more. Viruses, in particular, are prime candidates for causing major pandemics. Scientists estimate that there are around 1.7 million undiscovered viruses currently infecting mammals and birds, with approximately 40% of them capable of spilling over to humans. By incorporating this information, as well as data on global population, air travel networks, community movements, preparedness levels, and human responses, scientists built a model that generated virtual pandemics. Based on this catalog, they estimated the probability of another COVID-19-level pandemic to be between 2.5% and 3.3% per year.

To grasp how these risks translate over a lifetime, let's consider a value around the middle of these estimates: 2%. Using a probability tree diagram to model all possible scenarios, we find that the likelihood of living through at least one more COVID-19-level pandemic in the next 75 years is 78%. Even with the most optimistic yearly estimate of 0.5%, the probability drops to 31%, while the most pessimistic estimate raises it to 92%. These probabilities are too significant to ignore, as future generations might not be as fortunate as we have been. Additionally, pandemics are random, independent events, meaning that even with a 1% yearly probability, we could still face another pandemic within a decade.

Fortunately, we now possess tools that can mitigate the impact of pandemics. Early warning systems, contact tracing, social distancing, and other public health measures have already saved numerous lives during the COVID-19 pandemic, not to mention the significant role vaccines have played. While another pandemic is inevitable, we can work to reduce the likelihood of spillover events and effectively contain them to prevent widespread pandemics. By exercising greater caution in our interactions with the animal world and implementing well-funded, open-access global disease monitoring programs, AI-powered contact tracing and isolation measures, universal vaccines, next-generation antiviral drugs, and other innovative technologies, we can alter these probabilities. The choice lies before us I I I I I I I. I i I

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